Assistant Laboratory Animal Technician (ALAT) Practice Exam

Question: 1 / 575

What is the primary reason immunodeficient animals require barrier conditions?

High genetic variability

Increased susceptibility to infections

Immunodeficient animals require barrier conditions primarily due to their increased susceptibility to infections. These animals have compromised immune systems, making them highly vulnerable to pathogens that would not typically affect healthy animals. By maintaining barrier conditions, it is possible to control the environment around the animals, minimizing their exposure to potential infectious agents.

This controlled environment often includes features such as filtered air systems, sterilized bedding, and provisions that limit contact with other animals or human handlers to reduce the risk of introducing pathogens. The goal is to protect these sensitive animals from infections that could significantly impact their health and affect the validity of research results.

Understanding the increased susceptibility to infections is crucial, as it highlights the importance of rigorous biosecurity measures in laboratories that house immunodeficient animals. These practices ensure the integrity of research findings and the overall welfare of the animals involved.

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Necessity for genetic purity

Ethical considerations in breeding

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